EKFC creatinine eGFR (2021)

Estimates GFR from serum creatinine using the European Kidney Function Consortium (EKFC) creatinine equation (Pottel et al., 2021). Valid across the full age spectrum (2-120 years).

Usage

egfr_ekfc_cr(
  creatinine,
  age,
  sex,
  creatinine_units = "mg/dl",
  label_sex_male = "male",
  label_sex_female = "female",
  q = NULL
)

Arguments

creatinine

Numeric vector of serum creatinine.

age

Numeric vector of age in years.

sex

Vector of sex labels (see label_sex_male/label_sex_female).

creatinine_units

Units of creatinine: "mg/dl" (default) or "umol/l".

label_sex_male, label_sex_female

Values in sex that denote male and female records. Defaults to "male"/"female".

q

Optional numeric vector of the reference creatinine Q value (median creatinine for the age/sex, in mg/dL). When NULL (the default) the built-in EKFC reference Q is used; supply a value to use a population-, assay-, or individual-specific Q. Recycled to the length of the other inputs.

Value

Numeric vector of eGFR in mL/min/1.73m^2.

References

Pottel H, Bjork J, Courbebaisse M, et al. Development and validation of a modified full age spectrum creatinine-based equation to estimate glomerular filtration rate. Ann Intern Med. 2021;174(2):183-191. doi:10.7326/M20-4366

Examples

egfr_ekfc_cr(creatinine = 1.0, age = 50, sex = "female")
#> [1] 64.80412
egfr_ekfc_cr(0.5, 8, "male")
#> [1] 76.30799
egfr_ekfc_cr(1.0, 50, "female", q = 0.72)
#> [1] 66.904