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Estimates GFR from serum creatinine using the IDMS-traceable 4-variable MDRD Study equation (Levey et al., 2006). Historical; superseded by CKD-EPI for clinical use.

Usage

egfr_mdrd(
  creatinine,
  age,
  sex,
  ethnicity = NULL,
  creatinine_units = "mg/dl",
  label_sex_male = "male",
  label_sex_female = "female",
  label_afroamerican = c("black", "Black")
)

Arguments

creatinine

Numeric vector of serum creatinine.

age

Numeric vector of age in years.

sex

Vector of sex labels (see label_sex_male/label_sex_female).

ethnicity

Optional vector of ethnicity labels. Records matching label_afroamerican receive the Black race coefficient (1.159); all others receive 1.0. If NULL (default) no race coefficient is applied.

creatinine_units

Units of creatinine: "mg/dl" (default) or "umol/l".

label_sex_male, label_sex_female

Values in sex that denote male and female records. Defaults to "male"/"female".

label_afroamerican

Values in ethnicity denoting Black/African American race. Defaults to c("black", "Black").

Value

Numeric vector of eGFR in mL/min/1.73m^2.

References

Levey AS, Coresh J, Greene T, et al. Using standardized serum creatinine values in the MDRD study equation. Ann Intern Med. 2006;145(4):247-254. doi:10.7326/0003-4819-145-4-200608150-00004

Examples

egfr_mdrd(creatinine = 1.2, age = 60, sex = "male")
#> [1] 61.75871