Neonatal creatinine eGFR (2022) — egfr

Estimates GFR in term-born neonates using the updated Schwartz-type coefficient of Smeets et al. (2022). Requires IDMS-standardised creatinine.

Usage

egfr_neonatal(
  creatinine,
  height,
  creatinine_units = "mg/dl",
  height_units = "cm"
)

Arguments

creatinine: Numeric vector of serum creatinine.
height: Numeric vector of height.
creatinine_units: Units of creatinine: "mg/dl" (default) or "umol/l".
height_units: Units of height: "cm" (default) or "m".

Value

Numeric vector of eGFR in mL/min/1.73m^2.

Validity

Derived for term-born neonates (gestational age >= 37 weeks) over postnatal days 0-28. The authors explicitly note it is not intended for preterm neonates, and that validation in a large neonatal cohort is still required.

References

Smeets NJL, IntHout J, van der Burgh MJP, Schwartz GJ, Schreuder MF, de Wildt SN. Maturation of GFR in term-born neonates: an individual participant data meta-analysis. J Am Soc Nephrol. 2022;33(7):1277-1292. doi:10.1681/ASN.2021101326

Examples

egfr_neonatal(creatinine = 0.5, height = 50)
#> [1] 31